Scientist I, Tissue Material Sciences (Device Biology Research)

Technical expert that will, under supervision, develop and execute in vivo models, as well as perform a range of cell and tissue-based in vitro assays to support the development and differentiation of implantable biomaterials in support of Allergan Aesthetics’ Medical Device franchises.  Techniques employed will include intradermal and subcutaneous injection in small or large animals, 3D imaging, histology, microscopy, as well as common practices in cell and molecular biology, such as cell culture, PCR, and ELISA.  Proficiency in in vivo animal handling and care, as well as good overall working knowledge of common laboratory techniques in a BSL 2 environment is essential. It is also expected that the incumbent has the ability to innovate and implement new experimental protocols, demonstrate mastery of broad range of experimental techniques, and appropriately document experimental findings. Additional day to day activities may include statistical analysis of results, staying current in the relevant therapeutic areas with routine reading and application of relevant scientific literature, and lab support activities including procurement and general lab organization. 

The employee must conduct their work activities in compliance with all AbbVie, Irvine internal requirements and with all applicable regulatory requirements, including knowledge of operating in a controlled environment per the requirements of 21 CFR 820, ISO 13485 and ISO 14971.  AbbVie, Irvine internal requirements include compliance with ethics, environmental health and safety, financial, human resources, and general business policies, requirements and objectives.

Develop and execute in vivo and in vitro assays to evaluate the tissue response to implantable biomaterials 60%

Analysis and interpretation of results including documentation and preparing summaries of results and methods 30%

Innovate and implement new experimental protocols 10%