Senior Research Associate, Pharmacology

Company Summary:

FL87, Inc. is a privately held, early-stage biotechnology company developing a novel approach to gene therapy that can address currently untreatable diseases.

FL87 was founded by Flagship Pioneering, an innovation enterprise that conceives, creates, resources, and grows first-in-category life sciences companies. Flagship Pioneering has created over 100 groundbreaking companies over the past twenty years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna (MRNA), Syros Pharmaceuticals (SYRS), Seres Therapeutics (NASDAQ:MCRB), Generate Biomedicines, Tessera Tx, Evelo Biosciences (EVLO), and Indigo Agriculture.

Position Summary:

We are searching for a motivated Sr. Research Associate to drive in vivo studies for platform development and therapeutic proof-of-principle. More broadly, we are looking for an individual who enjoys working with animal models and brings scientific rigor, intellectual curiosity, enthusiasm, and a desire to innovate new nucleic acid therapeutics. This individual will have the opportunity to work in a dynamic and fast-paced entrepreneurial environment, working as part of a highly collaborative and rapidly growing team.

Key Responsibilities:

• Execute and analyze animal experiments to assess in vivo efficacy, safety, and PK/PD profiles of novel nucleic acid therapeutics.
• Support the design and execution of method development and pilot experiments to test specific hypotheses and drive R&D efforts with guidance.
• Maintenance of electronic lab notebooks and timely documentation of data
• Provide support in additional in vitro assays as needed.
• Ensure rapid documentation of all results and observations without compromising data integrity or scientific accuracy.
• Effectively communicate experimental findings in oral, written, and visual formats.
• Work independently and collaboratively in a multidisciplinary team environment.

Qualifications:

• BS with 5+ or MS in relevant discipline with 3+ years of industry experience.
• Experience executing in vivo studies, ideally involving gene delivery and/or nucleic acid based therapeutics in rodents.
• Experience dosing therapeutics via intravenous, intraperitoneal, intramuscular, and subcutaneous routes of administration.
• Experience collecting materials (blood, tissue, etc.) and supporting processing and execution of ex vivo bioanalytics.
• Experience with various rodent models of diseases is a plus.
• Strong communication and interpersonal skills.
• Demonstrated ability to work effectively in a team environment, working closely cross-functionally to achieve shared objectives.
• Strong organizational, analytical, and problem-solving skills.
• Strong understanding of the scientific method and its application in a biotech setting to drive development and innovation with data rigor
• Welcome new challenges and maintain productivity and quality in a high-energy, rapidly growing  biotech environment.

About Flagship 

Flagship Pioneering is a biotechnology company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.  

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background. 

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto. 

The salary range for this role is $81,000 - $107,250. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. FL87 currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on FL87's good faith estimate as of the date of publication and may be modified in the future.