Senior Product Manager - 1 Year FTC (we have office locations in Cambridge, Leeds and London)

We’re hiring a Senior Product Manager to take strategic ownership of live, national-scale genomics products and shape the future of the Generation Study.

What we're doing 

The Generation Study is one of Genomics England's most ambitious programmes - a national study exploring how whole genome sequencing can improve the diagnosis of rare genetic conditions in newborn babies and providing evidence to inform the governments future strategy on genomic newborn sequencing. We've built the products that make it work and they are running at scale. Now we need someone to own them through the next - and arguably the most strategically interesting - phase of the study. 

The Products 

You'll take strategic ownership of three live products that form the operational backbone of the Generation Study: 

• The Generation Study Portal - the intake tool through which participants enter the study and which currently holds the contact, demographics and consent information 

• The Bioinformatic Pipeline - the engine that processes whole genome sequencing data at scale and prioritises variants 

• The Variant Review Tool - the interpretation product used by clinicians to review genomic findings and generate reports for the NHS consultants 

All three products are live and at a stable point in their lifecycle. Feature development is less intense now, focused mainly on iterative changes that are critical to the continued success of mission. This role has an opportunity to spend some time looking ahead strategically and think carefully about what comes next. 

The Squad 

You'll be the Product Lead for the NII (Newborns Intake and Interpretation) Squad - a newly merged team that previously operated as three separate squads. The squad is fresh, the ways of working are still being established, and you'll be working alongside a new squad coach who will handle day-to-day squad operations. This is a moment of real transition, and the right person will find that energising rather than unsettling. 

What makes this role unusual 

The Generation Study is halfway through recruitment and will finish this early 2027 - what happens after that is genuinely open. It might mean evolving the products to support closedown of study processes followed by sunsetting and migrating their data capabilities into longer-lived Genomics England infrastructure. It might mean a managed lessons-learned process as the study concludes and understanding what components could transfer into a next phase. It might mean something more expansive: evolving these products into a new platform for APGP, supporting a reanalysis of samples against a childhood panel, or building remote consent capability for a new phase of the study. It could be elements of all of this.  

We don't know yet. When we do know, it will need to happen quickly and to a high standard. 

We need someone who can hold the live products steady, build trust with a newly merged squad, and be ready to think and move strategically - in whichever direction the mission requires. You'll need to draw on resources across Genomics England, spot and investigate parallels with other programmes, and work out the best path forward from first principles when the time comes. 

If that kind of strategic ambiguity sounds like an opportunity rather than a problem, you are the kind of person we are looking for. 

What you'll be doing 

• Holding strategic ownership of the GSP, bioinformatic pipeline, and VRT - ensuring they run reliably and that any critical changes are well-considered and well-executed 

• Helping a newly merged squad find its feet - establishing shared ways of working alongside a new squad coach, and creating the conditions for the team to do its best work 

• Staying close to the study's direction of travel, building relationships across Genomics England, and positioning the squad to move quickly when the path forward becomes clear 

• Thinking across possible futures - sunset, migration, evolution, new capability - and being ready to develop and execute a credible strategy for whichever materialises 

• Managing stakeholders with clarity and confidence, being transparent about priorities, trade-offs, and uncertainty 

• Mentoring and supporting team members, and contributing to product management practice across Genomics England 

What we're looking for 

Essential: 

• Experienced Senior Product Manager, comfortable owning complex products in live, production environments 

• Strategic thinker who can operate effectively under uncertainty and pivot when direction changes 

• Strong understanding of data products and backend systems - able to go deep with engineers when it matters 

• Excellent stakeholder management - able to hold credibility at senior levels while remaining genuinely collaborative 

• A natural connector - someone who seeks out parallels, draws on expertise from across an organisation, and builds the relationships needed to make things happen 

• Calm, grounded, and proactive - someone who figures things out rather than waiting to be told what to do 

• Experience leading and mentoring teams, and creating collaborative environments where people do their best work 

Preferred: 

• Experience managing product close-down, migration, or transition - including sunsetting products responsibly 

• Experience with complex data pipelines or bioinformatic / scientific software products 

• Scientific background - comfortable with biological or clinical language and engaging with genomics concepts 

Prior genomics experience is not required. The focus is on strategic product management capability and the confidence to operate well in ambiguity. 

Why this role 

The Generation Study is asking whether genomic sequencing could become a routine part of newborn care - catching rare conditions earlier and changing outcomes for families. The products you'll own are what make that possible right now, at national scale. 

As Senior Product Manager, you'll inherit live, meaningful systems, help a new team find its shape, and play a genuine part in determining what the Generation Study leaves behind - for patients, for the NHS, and for the programmes that come after it.